Javier Murillas 1, Antonio Rimola 2 3, Montserrat Laguno 2, Elisa de Lazzari 2, Javier Rascn 1, Fernando Aguero 2, Jose L. In contrast better survival has been reported in non-HIV-infected patients with cirrhosis of different etiologies after the onset of hepatic decompensation (74%-90% at 1 year and 65%-80% at 2 years).' After the first major clinical decompensation of their liver disease, our patients had a survival probability of 57% at 1 year of follow-up and 41% at 2 years. 'This prospective study showed that HIV-1-infected patients with ESLD had a rapid progression to death and confirmed the high mortality rates reported in previous retrospective studies in patients coinfected with HIV and HCV. However, because only a small proportion of the patients in this study were considered candidates for liver transplantation and most died while on the waiting list, few received a transplant.' The MELD score may be useful in deciding whether to indicate liver transplantation in these patients.

'In conclusion, HIV-1-infected patients with ESLD, especially those with poorly controlled HIV and a high MELD score, have a poor short-term outcome. 'it might also be suggested that liver transplantation in HIV-infected patients should be indicated earlier than in non-HIV-infected patients' The model for end-stage liver disease score (MELD) is the best prognostic factor in HIV 1-infected patients with end-stage liver disease: A prospective cohort study

Meld score 12